Multiple Myeloma

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Condition treated at:

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KK Women's and Children's Hospital

Blood Cancer Centre
Haematology
Department of Haematology

Multiple Myeloma - Diagnosis

How is multiple myeloma diagnosed?

Several tests and procedures might be needed to diagnose myeloma and develop an effective treatment plan.

These may include:

Clinical examination: Your doctor will check for any myeloma related complications and assess baseline functional capacity of different organ systems.
Blood tests: To test blood cell, kidney and liver function assessments. Blood tests required for measurement of M protein, subtyping and quantification as well as investigations required for staging like beta-2 microglobulin, to assess the extent of complications or organ function effects like kidney, calcium level etc will be performed.
Bone marrow aspiration and biopsy: Bone marrow samples are usually taken by inserting a needle into the flat part of the hip bone to extract the samples. These are then examined in the laboratory for the presence of cancer cells. It will also help quantify the percentage of the cancer cells in the marrow and help with prognostication by seeking the genetic change that the cancer cells harbour.
Imaging tests: Imaging tests including X-Rays or CT scan, MRI scans of the back bones and PET scans may be used to look for extent of the bone destruction caused by myeloma in the body.

Article contributed by Haematology, Singapore General Hospital

The information provided is not intended as medical advice. Terms of use. Information provided by SingHealth

Clin Prof Ng Heng Joo

Head ＆ Senior Consultant

MBBS, MMed (Int Med), MRCP(UK), FRCPath(UK),FAMS

Clinical Interests: Thrombosis and Haemostasis, Laboratory Haematology

Clin Assoc Prof Chandramouli Nagarajan

Senior Consultant

MBBS, FRCP(Edin), FRCPath(UK)

Clinical Interests: Lymphoma, Myeloma

Dr Chen Yunxin

Senior Consultant

MBBS, MRCP(UK), FRCPath(UK)

Clinical Interests: Lymphoma, Myeloma

Assoc Prof Charles Chuah

Senior Consultant

MBChB, MMed(Int Med), MD(London), FRCP(Edin)

Clinical Interests: Myeloproliferative Neoplasm, Chronic Myeloid Leukemia

Dr Denise Tan Yan

Senior Consultant

MBBS (Singapore), MRCP (UK), MMed (Internal Medicine), FRCPath (UK)

Clinical Interests: General Haematology, Myeloproliferative Neoplasm

Dr Nicholas Grigoropoulos

Senior Consultant

MBBS, PhD, MRCP(UK), FRCPath(UK)

Clinical Interests: Lymphoma

Clin Prof Goh Yeow Tee

Senior Consultant

MBBS, M Med (Int Med)

Clinical Interests: Stem Cell Transplantation, Lymphoproliferative Disease, Myeloma

Dr Than Hein

Senior Consultant

MBBS, MRCP(UK), MMed(Int Med), FRCPath(UK), FAMS

Clinical Interests: Acute Leukemia, Myeloproliferative Neoplasm, Haematopoietic Stem Cell ＆ Cellular Therapy

Dr Ho Liam Pock

Senior Consultant

MBBS, FRCPA

Clinical Interests: Haematopathology

Prof William Hwang

Senior Consultant

MBBS, M Med(Int Med), FRCP(London), FAMS

Clinical Interests: Haematopoietic Stem Cell ＆ Cellular Therapy

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