Multiple Myeloma

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Department of Haematology

Multiple Myeloma - Causes and Risk Factors

What are the risk factors for multiple myeloma?

There is no specific cause for myeloma, but some factors that can increase the risk of myeloma include:

Age – Myeloma is more common in people over the age of 55 and increases with age such that over the age of 80 years up to 5% of patients may have myeloma.
Gender – Males are slightly more likely to develop myeloma compared to females.
Repeated exposure to toxic elements such as agricultural chemicals or pesticides, and petrochemicals are thought to increase the risk of Myeloma.
Exposure to DNA damaging ionising radiation or chemotherapeutic agents
Obesity is a common risk factor for several forms of cancers, including Myeloma

People with a first degree relative (a parent, sibling, or child) with Myeloma are nearly two times more likely to develop it compared to the general population

Article contributed by Haematology, Singapore General Hospital

The information provided is not intended as medical advice. Terms of use. Information provided by SingHealth

Clin Prof Ng Heng Joo

Head ＆ Senior Consultant

MBBS, MMed (Int Med), MRCP(UK), FRCPath(UK),FAMS

Clinical Interests: Thrombosis and Haemostasis, Laboratory Haematology

Clin Assoc Prof Chandramouli Nagarajan

Senior Consultant

MBBS, FRCP(Edin), FRCPath(UK)

Clinical Interests: Lymphoma, Myeloma

Dr Chen Yunxin

Senior Consultant

MBBS, MRCP(UK), FRCPath(UK)

Clinical Interests: Lymphoma, Myeloma

Assoc Prof Charles Chuah

Senior Consultant

MBChB, MMed(Int Med), MD(London), FRCP(Edin)

Clinical Interests: Myeloproliferative Neoplasm, Chronic Myeloid Leukemia

Dr Denise Tan Yan

Senior Consultant

MBBS (Singapore), MRCP (UK), MMed (Internal Medicine), FRCPath (UK)

Clinical Interests: General Haematology, Myeloproliferative Neoplasm

Dr Nicholas Grigoropoulos

Senior Consultant

MBBS, PhD, MRCP(UK), FRCPath(UK)

Clinical Interests: Lymphoma

Clin Prof Goh Yeow Tee

Senior Consultant

MBBS, M Med (Int Med)

Clinical Interests: Stem Cell Transplantation, Lymphoproliferative Disease, Myeloma

Dr Than Hein

Senior Consultant

MBBS, MRCP(UK), MMed(Int Med), FRCPath(UK), FAMS

Clinical Interests: Acute Leukemia, Myeloproliferative Neoplasm, Haematopoietic Stem Cell ＆ Cellular Therapy

Dr Ho Liam Pock

Senior Consultant

MBBS, FRCPA

Clinical Interests: Haematopathology

Prof William Hwang

Senior Consultant

MBBS, M Med(Int Med), FRCP(London), FAMS

Clinical Interests: Haematopoietic Stem Cell ＆ Cellular Therapy

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