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Systemic Sclerosis (Scleroderma)

Systemic Sclerosis (Scleroderma) - Symptoms

The first sign of scleroderma is usually the development of areas of thickened or hard skin around the joints of the fingers and toes. This hardened skin tends to lead to skin tightening that may decrease joint mobility. There may be intense skin itching and inflammation.

Patients may also experience symptoms such as joint pain and swelling (similar to arthritis), shortness of breath or persistent coughing (if the lungs are affected), fatigue with very high blood pressure (if the kidneys are affected), chest pains or irregular heart beat (if the heart is affected), heartburn, swallowing difficulties, bowel constipation, diarrhoea or weight loss (if the digestive system is affected) and dry mouth and eyes (if salivary glands and tear ducts are affected). Dental health may be compromised due to difficulty in opening the mouth caused by tight facial skin and dry mouth may lead to tooth decay.

Our Care Team

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Andrea Low Assoc Prof

Assoc Prof Andrea Low

Senior Consultant

​BmedSci (UK), BMBS (UK), MRCP (UK), FAMS (Rheumatology), MCI

Clinical Interests: Systemic Sclerosis (Scleroderma)

Cassandra Hong Dr

Dr Cassandra Hong

Senior Consultant

​MBChB (Edin), MRCP (London), MRCP (Rheumatology), MSc in Rheumatology (King’s College London)

Clinical Interests: Musculoskeletal Ultrasound, Systemic Sclerosis (Scleroderma), Psoriatic Arthritis

Sue-Ann Ng Dr

Dr Sue-Ann Ng

Senior Consultant

​MBBS, BSc (Med), MRCP(UK)

Clinical Interests: Systemic Sclerosis (Scleroderma)

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