Aplastic Anaemia

Aplastic Anaemia - Treatments

How is aplastic anaemia treated?

Patients with mild aplastic anaemia and have no symptoms will be managed with close observation.

A person with more severe aplastic anaemia may require regular transfusions of red blood cells and platelets, and may need to take medications to reduce the risk of infection. Some patients may receive treatment with drugs called androgens to try to stimulate their bone marrow, whilst others may require treatment with medications to suppress the immune system (e.g. ciclosporin, anti-thymocyte globulin) and specific drugs to stimulate blood cell production (e.g. eltrombopag).

In certain circumstances where the aplastic anaemia is severe and there is a full-matched donor, a haemopoietic stem cell transplant may be recommended.

Regardless of the treatment, most patients with aplastic anaemia will be followed-up lifelong in our Specialist Clinic to monitor for relapses and treat long term complications of the condition.

Haematopoietic Stem Cell Transplant,

Antithymocyte Immunoglobulin (horse),

Ciclosporin (Cyclosporine),

Etrombopag

Article contributed by Haematology, Singapore General Hospital

The information provided is not intended as medical advice. Terms of use. Information provided by SingHealth

Clin Prof Ng Heng Joo

Head ＆ Senior Consultant

MBBS, MMed (Int Med), MRCP(UK), FRCPath(UK),FAMS

Clinical Interests: Thrombosis and Haemostasis, Laboratory Haematology

Clin Assoc Prof Chandramouli Nagarajan

Senior Consultant

MBBS, FRCP(Edin), FRCPath(UK)

Clinical Interests: Lymphoma, Myeloma

Dr Jason Chay Wai Mun

Senior Consultant

MBBS (Singapore), MRCP (UK), FRCPath Haematology (UK), FAMS (Singapore), GDFM (Singapore)

Clinical Interests: Transfusion Medicine, Laboratory Haematology

Dr Chen Yunxin

Senior Consultant

MBBS, MRCP(UK), FRCPath(UK)

Clinical Interests: Lymphoma, Myeloma

Assoc Prof Charles Chuah

Senior Consultant

MBChB, MMed(Int Med), MD(London), FRCP(Edin)

Clinical Interests: Myeloproliferative Neoplasm, Chronic Myeloid Leukemia

Dr Denise Tan Yan

Senior Consultant

MBBS (Singapore), MRCP (UK), MMed (Internal Medicine), FRCPath (UK)

Clinical Interests: General Haematology, Myeloproliferative Neoplasm

Dr Nicholas Grigoropoulos

Senior Consultant

MBBS, PhD, MRCP(UK), FRCPath(UK)

Clinical Interests: Lymphoma

Clin Prof Goh Yeow Tee

Senior Consultant

MBBS, M Med (Int Med)

Clinical Interests: Stem Cell Transplantation, Lymphoproliferative Disease, Myeloma

Dr Than Hein

Senior Consultant

MBBS, MRCP(UK), MMed(Int Med), FRCPath(UK), FAMS

Clinical Interests: Acute Leukemia, Myeloproliferative Neoplasm, Haematopoietic Stem Cell ＆ Cellular Therapy

Dr Ho Liam Pock

Senior Consultant

MBBS, FRCPA

Clinical Interests: Haematopathology

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