Hyponatremia: Approach to Diagnosis and Management
29 September 2021
Hyponatremia, defined as a serum sodium concentration below 135mEq/L, is the most common electrolyte disorder seen in clinical practice. Though it is often mild and asymptomatic, severe, symptomatic hyponatremia can result in significant morbidity and mortality in the hospitalized patient. Hypo-osmolar hyponatremia is characterised by the presence of excess total body water relative to total body solute; this state underpins the multiple etiologies of hyponatremia. Syndrome of inappropriate secretion of anti-diuretic hormone (SIADH) is a disorder of impaired water excretion caused by the inability to suppress ADH secretion. Amongst other causes, several medications have been found to be associated with SIADH and cessation of these drugs, where possible, reverses the underlying ADH excess. While fluid restriction and maintaining adequate solute intake remain the mainstay of treatment, vasopressin receptor antagonists (vaptans) may have a role to play in specific circumstances.
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Lecture DetailsDate:29 September 2021, WednesdayTiming:6.30 pm - 7.30 pmDuration:60 minutesFees:ComplimentaryPlatform:Zoom Cloud MeetingsRegistration Closing Date:30 August 2021, MondayTarget Audience:Pharmacist(Zoom Capacity: 500
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