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Micronised Progesterone

Drug Class: Commonly Known As: Category:
Progesterone Utrogestan

Micronised Progesterone - What is it for

Micronised progesterone (also known and Utrogestan®) is a type of progestogen that can be used for the following purposes:​

  • Preparing the uterus for implantation of a fertilized egg, where the egg sticks to the wall of uterus
  • Maintenance of pregnancy once implantation occurs
  • Enhance implantation of a fertilized egg (routinely used during in vitro fertilization (IVF)) and to decrease the risk of spontaneous abortion (miscarriage)
  • Management of various abnormal uterine bleeding including absence of menstrual flow and heavy menstrual bleeding
  • Management of menopause in combination with estrogen replacement therapy
It is important to use micronised progestogen as directed by your healthcare professional.

Micronised Progesterone - Side Effects, Precautions, and Contraindications

What side effects can Micronised Progesterone cause?

Common side effects include:
  • Stomach discomfort, nausea and vomiting
    • If taken by mouth, take after food to reduce these side effects.
  • Breast tenderness
  • Headache
    • You may take Paracetamol to manage headaches.
  • Dizziness, drowsiness
    • Avoid activities that require mental alertness and avoid using heavy machineries.
  • Weight changes, mood swings
    • Take medication at the same time every day to avoid huge changes in the hormone levels in your body, which can lead to mood changes.
  • Skin pigmentation
    • Apply sunblock when outdoors and avoid long hours of sun exposure.

Inform your doctor if these side effects become severe and bothersome.

The symptoms of a drug allergy include one or more of the following:

  • Swollen face/eyes/lips/tongue
  • Difficulty in breathing
  • Itchy skin rashes over your whole body

If you experience any of these symptoms, you should stop your medication and see your healthcare professional immediately.

Before taking Micronised Progesterone , what precautions must I follow?

​Inform your healthcare professional if:

  • You are allergic to this medication or any of the other ingredients of this medication.
  • You are taking any other medications, including supplements, traditional medications and herbal remedies.
  • You have a history of or current medical conditions such as liver problems, stroke, heart disease, blood clots, migraine headaches, epilepsy (fits), diabetes mellitus or cancer.

What food or medicine must I avoid when I take Micronised Progesterone ?

  • ​Some medications might interact with this medication. Check with your healthcare professional if you want to take any other medicines, supplements or herbal products. 
  • If you see another healthcare professional, inform him that you are taking this medication before he prescribes any other medications.

Micronised Progesterone - Dosage and How to Use

How should Micronised Progesterone be used?

  • ​Do not stop taking your medication without checking with your healthcare professional.
  • This medicine can be taken by mouth or inserted into the vagina. Please refer to the medication label for specific instructions. 
  • The medicine should be taken after food, if taken by mouth.

What should I do if I miss a dose?

​If you forget to take a dose, take it as soon as you remember. Then take your next dose at the usual time. Do not take two doses to make up for the missed dose.

Micronised Progesterone - Storage

How should I store Micronised Progesterone ?

  • Keep away from children
  • Keep in a cool, dry place, away from direct sunlight

How should I dispose of Micronised Progesterone safely?

​Pack this medication into a black trash bag and seal it tightly before throwing into the rubbish chute or bin.

  • Updated on 31 October 2022
  • Article contributed by PSS National Medication Information Workgroup , PSS National Medication Information Workgroup
The information provided is not intended as medical advice. Terms of use. Information provided by SingHealth

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