Thioguanine is an anticancer medication used in the treatment of leukemia. It works by interfering with the deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) production.
Possible side effects from Thioguanine and their management are listed below. Always inform the doctor if you experience any side effects, so that the necessary monitoring may be conducted. Seek immediate medical attention if side effects are serious and urgent.
Low white blood cell counts.
White blood cells protect the body by fighting bacteria (germs) that cause infection. When the number of white blood cells is low, your child will be more susceptible to infections and may become very ill from these infections.
To help prevent infection:
Low platelet counts.
Platelets are important for blood clotting. With low platelets, your child may bruise or bleed (for e.g. gums or nose) more easily than usual.
Be safety conscious.
Brush teeth gently with a soft-bristled toothbrush.
Low red blood cell counts.
Red blood cell transport oxygen to body cells. Your child may feel tired or lethargic if red blood cell is low.
Liver problems.
Mild, transient changes to liver function may occur.
Your doctor will monitor liver function using blood tests during therapy, and make adjustment to the therapy if necessary.
In the rare event that yellowing of skin and/ or eye(s), dark coloured urine, pale coloured stools, or pain in the upper stomach occurs, seek medical help immediately.
Nausea, vomiting, loss of appetite or diarrhea may rarely happen.
