Olaparib

• Nausea and vomiting
• Diarrhea and/or stomach discomfort
• Constipation
• Decreased appetite and taste changes
• Headache, bone, muscle or back ache
• Fatigue
• Rash
• Decreased blood cells
  This may increase your chances of getting infections, bruising or bleeding. You may also feel tired with a general lack of energy; do avoid over-exerting yourself with strenous physical activities.

Inform your doctor if any of the following occurs:

• Unhealthy pale skin appearance, increasing tiredness or weakness, light-headedness
• Persistent weight loss
• Signs of infection – fever, chills, cough, sore throat
• Unusual bruising or bleeding, black sticky stools or blood in the urine
• Suden onset or worsening of cough with chest pain or breathing difficulty

• Inform your doctor of pharmacist if you:
• Have any other medical conditions e.g kidney or lung problems
• Are taking any other medication, herbal products or supplements
• Use effective birth control during and after stopping treatment for at least:
• 1 month (for women)
• 3 months (for men)

Inform your doctor if you or your partner plan for or suspect pregnancy.

• Avoid the following fruit and their juices while taking Olaparib:
• Grapefruit
• Pomelo
• Seville orange

Take Olaparib twice daily at approximately the same time each day. Take the exact number of tablets / capsules as instructed by your doctor. Swallow the tablets / capsules whole.  

For tablets: Take with or without food.

For capsules: Take 2 hours before food or 1 hour after food.

If you miss a dose of Olaparib, skip the missed dose and resume your usual dosing time. Do not make up for the missed dose or take two doses at once.

If you overdose on this medication, inform your doctor immediately.

Do not crush, chew or break the tablets / capsules.

​For tablets: Store at room temperature, in a cool, dry place away from direct sunlight.

For capsules: Store in the refrigerator. Do  not freeze.