Mercaptopurine is a medication used in the treatment of inflammatory bowel disease such as Crohn’s disease or ulcerative colitis and other autoimmune diseases. It belongs to a class of drugs known as immunosuppressants. It works by interfering with the deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) production. By interfering with DNA and RNA, Mercaptopurine reduces the activity of the immune system.