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Ethosuximide

Drug Class: Commonly Known As: Category:
Zarontin

Ethosuximide - What is it for

Ethosuximide is used to control seizures (fits).

Ethosuximide - Side Effects, Precautions, and Contraindications

What side effects can Ethosuximide cause?

Like all medicines, this medication may cause some possible side effects but not everyone experiences them. Consult your healthcare professional if any of the side effects lasts more than a few days or become severe and bothersome.

The common side effects of Ethosuximide include:

  • Dizziness
    • Get up slowly from sitting or lying down position
  • Drowsiness
    • Avoid driving or engaging in activities that requires concentration
  • Diarrhoea
    • Drink more water to replace loss of fluids
  • Nausea, vomiting
    • Take the medicine with or after food to reduce nausea and vomiting
    • Avoid food that is too rich, spicy or has strong smells
  • Headache
    • Take Paracetamol if needed to relieve headache
  • Loss of appetite, abdominal pain
  • Hiccups
  • Poor muscle coordination

If the following serious side effects happen, you should consult your healthcare professional immediately:

  • Blistering, peeling, red skin rash due to Stevens-Johnson syndrome (SJS) and Toxic Epidermal Necrolysis (TEN)
    • SJS and TEN are rare and serious skin reactions. Symptoms include face swelling, blisters on skin, skin rashes that spread within hours to days. It usually occurs within the first few months (monitor closely for the first 3 months) of treatment.
    • As SJS and TEN progress rapidly, please consult your healthcare professional if you show the first sign of a rash.
  • Unusual bleeding and bruising
  • Prolonged fever, sore throat and mouth sores
  • Rash, joint swelling, swelling at neck and armpits
  • Unusual movement disorders

In rare cases, this medication may cause the following changes to a person’s mental condition, especially in the first few weeks of treatment or during dose changes:

  • Worsening agitation, restlessness, violent behaviour
  • New or worsening thoughts of harming yourself or ending your life
  • Other changes in mood or behaviour

Please inform your doctor as soon as possible, or for your family or caregiver to inform your doctor if you are unable to seek treatment on your own.

Do not stop taking this medication on your own without discussing with your doctor.

It is important to note that your doctor has prescribed this medication as he/ she feels you will benefit more from taking this medication over the possible side effects that it may cause, which have a low chance of occurring. Most people take this medication without any such problems.

The symptoms of a drug allergy include one or more of the following:

  • Swollen face / eyes/ lips / tongue
  • Difficulty in breathing
  • Itchy skin rashes over your whole body

If you experience any of these symptoms, you should stop your medication and see your healthcare professional immediately.

Before taking Ethosuximide , what precautions must I follow?

Inform your healthcare professional if you have the following medical conditions before starting on Ethosuximide:

  • Any symptoms of depression and/or suicidal ideation
  • Drug allergies

For women: Tell your doctor if you are pregnant and/or breastfeeding. Your doctor would have discussed the potential benefits and side effects with continuing/starting this medication.

Consult your healthcare professional immediately if your seizures get worse or become different after you start on this medication.

Be careful when driving or operating machinery as this medication may cause drowsiness or reduction in your reaction to respond quickly to unexpected and sudden events.

What food or medicine must I avoid when I take Ethosuximide ?

Avoid drinking alcohol while taking this medication as it can cause excessive drowsiness.

Ethosuximide - Dosage and How to Use

How should Ethosuximide be used?

  • Follow the instructions on your medication label and take the medication as prescribed by your doctor.
  • You can take this medication with or after food.
  • If you are taking capsules, swallow the capsules with a glass of water.
  • If you are using oral syrup, shake the bottle well before using. Use a medicine spoon or graduated syringe provided to measure your medication. Do not use household spoons as they may not be accurate.
  • You may not experience any benefits immediately after starting the medication as it may take up to a few weeks before this medication can exert its full effects. You should continue to take your medication regularly as instructed by your doctor even if you feel well. Stopping your medication without informing your healthcare professional may cause your condition to worsen quickly.
  • Do not stop taking or adjust the dose of this medication without consulting your healthcare professional. Do not change brands or dosage forms of the medication without informing your healthcare professional.

What should I do if I miss a dose?

If you miss a dose, take the missed dose as soon as you remember. If it is almost time for your next dose, take only the usual dose. Do not double your dose or use extra medicine to make up for the missed dose.

What should I do if I overdose?

Ethosuximide - Handling

How should I handle Ethosuximide safely?

Ethosuximide - Storage

How should I store Ethosuximide ?

;#Keep away from children;#Keep in a cool, dry place, away from direct sunlight;#

How should I dispose of Ethosuximide safely?

Pack this medication into a black trash bag and seal it tightly before throwing it into the rubbish chute or bin.

Ethosuximide - Additional Information

  • Updated on 8/31/2021 12:00:00 AM
  • Article contributed by PSS National Medication Information Workgroup PSS National Medication Information Workgroup
The information provided is not intended as medical advice. Terms of use. Information provided by SingHealth

​​There are certain restrictions in the supply of Ethosuximide. Ethosuximide is not available in community/retail pharmacies and is only available in selected healthcare institutions via prescription from in-house doctors. Please check with your healthcare provider if they are able to supply it.

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