Dolutegravir is an anti-retroviral medication that prevents the replication of viruses. It reduces the amount of viruses (viral load) in the body and keeps it at a low level. It may also be given as post-exposure prophylaxis (PEP), which is a short course of a combination of different anti-retroviral medications to prevent infection after a possible exposure to the virus.
It is always given in combination with other anti-retroviral medications (combination therapy).