Once the fibroids are removed, the uterus resumes its normal structure. There remains a potential risk that some muscle cells may develop genetic changes leading to development of new fibroids. There is a 10-30 percent chance that new fibroids will develop after the myomectomy operation. There is obviously no recurrence of fibroids if a hysterectomy is performed.
Uterine fibroids are by nature non-cancerous tumours. The malignant form of fibroid is known as leiomyosarcoma. It is a very rare tumour developed from abnormal muscle cells unrelated to fibroids. It can occur in the uterus with existing fibroids or without fibroids. Development of malignancy within an existing fibroid is extremely rare and is not a consideration for decision for surgery on fibroids.
