Jaundice is yellow discoloration of tissues due to accumulation of bilirubin. Normal serum bilirubin ranges from 7-32 mmol/L but jaundice may not be detected clinically until the level exceeds 40mmol/L. Various mechanisms can contribute to jaundice, such as excess bilirubin production, impaired intrahepatic conjugation and secretion, or obstruction in bile flow.
