The treatment of essential thrombocythemia includes
Good control of pre-existing conditions such as high blood pressure, high cholesterol and diabetes mellitus also helps to decrease the risk of blood clot.
A healthy lifestyle including regular exercise and a healthy diet is also recommended.
In patients who require reduction of the platelet count, this can be achieved with medication: hydroxyurea, anagrelide, PEGylated interferon.
Young patients with no history of previous blood clots generally do not need medications to reduce the platelet count.