First Trimester Screening & Non-Invasive Prenatal Testing

First Trimester Screening & Non-Invasive Prenatal Testing - Causes and Risk Factors

Down syndrome arises due to the presence of extra genetic material (known as a “chromosome”) in a person’s cells. This additional genetic material affects the way the brain and body develop.

Women at higher risk of having a baby with Down syndrome include those:

Who are older when they get pregnant
Have a previous child with Down syndrome
Have siblings with Down syndrome

However, anyone can have a baby with Down syndrome, including women who are younger or who have no history of Down syndrome in the family.

Figure 1. Relationship of risk of Down syndrome with respect to maternal age.

Figure 1. Relationship of risk of Down syndrome with respect to maternal age.

Article contributed by Obstetrics ＆ Gynaecology, Singapore General Hospital

The information provided is not intended as medical advice. Terms of use. Information provided by SingHealth

Dr Jason Lim Shau Khng

Head ＆ Senior Consultant

MBBS (Spore), MMed (Spore), MRCOG (UK), FAMS

Clinical Interests: Urogynaecology, Andrology, Reproductive Medicine, Obstetrics ＆ Gynaecology

Dr Devendra Kanagalingam

Senior Consultant

MBBS (Spore), FRCOG (UK)

Clinical Interests: Maternal Fetal Medicine, High-risk Pregnancy, Intrapartum Care, Obstetrics ＆ Gynaecology

Assoc Prof Yong Tze Tein

Senior Consultant

MBBS, FRCOG, FAMS

Clinical Interests: Reproductive Medicine, Menopause, Adolescent Gynaecology, Obstetrics ＆ Gynaecology

Dr Lim Whui Whui

Consultant

MBBS, MRCOG(UK), MMed (O&G)

Clinical Interests: Obstetrics ＆ Gynaecology

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