Melioidosis treatment is often prolonged, associated with an intensive phase (2-6 weeks) of injectable antibiotic (intravenous ceftazidime, meropenem or imipenem) followed by oral eradication therapy (trimethoprim-sulfamethoxazole +/- doxycyline +/- amoxicillin-clavulanic acid) for 3-6 months.
