Careful monitoring of the mother during pregnancy and labour and appropriate and timely interventions if there are any signs of foetal distress reduces the risk of asphyxia. Timely and appropriate resuscitation at birth is essential at restoring oxygen supply to the brain and other organs. There is clear evidence that Cooling the baby (Therapeutic Hypothermia) for 72 hours after birth can limit the severity of brain injury. Ensuring that further injury to the vulnerable brain from low blood sugar, infection and seizures is limited prevents compounding of brain injury.