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Assoc Prof Tan Han Khim

MBBS, FRCP (Edin), MD, FAMS

Senior Consultant

Singapore General Hospital

Specialty: Renal Medicine

Clinical Interest: Haemodialysis, Critical Care Nephrology, Albumin Liver Dialysis, Blood Purification

Conditions Treated by this Doctor:
Acid Base Disorders, Fluid ＆ Electrolytes, Haemodialysis - Acute and Chronic, Insertion of Non-tunneled Hemodialysis Catheter, Renal Biopsy, Renal Biopsy, Renal Clearance Studies, Renal Retardation, Renal Stone Disease, Renal Transplant.

Clinical Appointments

Senior Consultant Renal Medicine Singapore General Hospital

Profile

Dr Tan Han Khim graduated with MBBS from the National University of Singapore in 1989, obtained the MRCP (UK) in 1995 and was conferred Doctor of Medicine (MD) by the National University of Singapore in 2005.

Education

Professional Appointments and Committee Memberships

Current professional interest is in the field of Critical Care Nephrology, Blood Purification, acute renal replacement therapy, artificial liver support and cytokine immunomodulation in severe sepsis. MARS liver dialysis at SGH was started up by Dr Tan Han Khim in 2002/03 as a pilot project to treat acute liver failure patients in collaboration with the General Surgical and Gastroenterology/Hepatology departments. MARS has now become standard artificial organ support in the intensive care units at SGH available to critically ill patients where indicated.

Awards

MOH HMDP Fellowship in Critical Care Nephrology at the Austin Hospital, Heidelberg, Victoria, Australia in 1998/99;
NMRC CRRT research grant in 2001, Singhealth Research Grant to start up MARS liver dialysis in 2002/03

Research Interests

Blood Purification in sepsis
Liver support in the ICU
Acute kidney injury (AKI)

Publications

Tan HK, Lim JS, et al. MARS therapy in critically ill patients with advanced malignancy: A clinical and technical report. Liver Int 2003;23:52-60.
Tan HK, Yang WS, et al. Anticoagulation minimization is safe and effective in albumin liver dialysis using the Molecular Adsorbent Recirculating System (MARS). Artif Organs 2007;31:193-199.
Yang WS, Tan HK, et al. Albumin dialysis in critically ill patients: use vs. omission of intra-dialytic heparin. Artif Organs 2008;32:411-416
Tan HK, Yang WS et al. Albumin dialysis without anticoagulation in high-risk patients: Safety with efficacy. Presented in abstract form as poster at the International Conference of the Transplantation Society (TTS) in August 2008, Sydney, Australia.

Research Trials

Tags: Renal Medicine, Haemodialysis, Critical Care Nephrology, Albumin Liver Dialysis, Blood Purification, Acid Base Disorders, Fluid ＆ Electrolytes, Haemodialysis - Acute and Chronic, Insertion of Non-tunneled Hemodialysis Catheter, Renal Biopsy, Renal Biopsy, Renal Clearance Studies, Renal Retardation, Renal Stone Disease, Renal Transplant