Profile
Dr Steven J. Mesenas graduated from the National University of Singapore with a Bachelor of Medicine, Bachelor of Surgery (MBBS) in 1990 and became a Member of the Royal Colleges of Physicians of the United Kingdom [MRCP(UK)] in 1995. He is also a fellow of the Academy of Medicine, Singapore. He started training in Gastroenterology at Singapore General Hospital in 1996 and has completed advanced fellowships in interventional endoscopy and endoscopic retrograde cholangiopancreatography (ERCP) at the Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands in 1999 – 2000 and endosonography (EUS) at St Thomas’ Hospital, London, UK in 2004 / 2005.
He has published in local and international journals on endosonography and therapeutic endoscopy. Dr Mesenas has been an invited demonstrator and moderator in several region endoscopic workshops and was the course director for the Endoscopy workshop of GI Hep 2007 (Singapore). He is currently Senior Consultant Gastroenterologist at Singapore General Hospital and Clinical Senior Lecturer, Yong Loo Lin School of Medicine. He was also Director of the Singapore General Hospital, Endoscopy Centre from 2006 to 2013 and specializes in gastroenterology, interventional and advanced endoscopic techniques like ERCP and EUS.
Education
- Fellow of the Academy of Medicine (Singapore) Gastroenterology(2000) – Academy of Medicine (Singapore)
- Member of the Royal Colleges of Physicians (United Kingdom)(1995) MRCP(UK) – Royal Colleges of Physicians (UK)
- Foreign Medical Graduate Examinations for Medical Sciences Part I and Part II (FMGEMS)(1993) - Examinations Commissions for Foreign Medical Graduates (United States of America)
- Bachelor of Medicine, Bachelor of Surgery(MBBS)(1990) – University of Singapore, Singapore
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Professional Appointments and Committee Memberships
- Adjunct Assistant Professor, Duke-NUS Medical School
- Clinical Senior Lecturer, NUS Yong Loo Lin School of Medicine
- Clinical Lecturer, National University of Singapore
- Clinical Teacher, National University of Singapore
- Medical Protection Society – Ordinary Member
- Academy of Medicine (Singapore) - Fellow
- Gastroenterological Society of Singapore – Ordinary Member
- General Medical Council (United Kingdom) – Medical Practitioner
- Singapore Medical Association – Ordinary Member
- SingHealth Duke-NUS Gala Dinner 2015 – Steering Committee
- SingHealth Cluster Implementation Workgroup (CIW) - Member
- KTPH SRE committee
- Member of the Workgroup to Review the Use of Departmental Funds
- Chairperson, Organising Committee, Singapore General Hospital, Division of Medicine Charity Concert
- SGH Committee for Sedation – Member
- Division of Medicine Teaching and Training Committee – Member
- Singapore Medical Council’s Complaint Panel
- Member of Board of Directors, The Singapore Lyric Opera Ltd
- Clinical Core Faculty Member – SingHealth Senior Residency Program
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Awards
- National Day Awards Long Service Medal
- Singapore Armed Forces Good Service Medal
- HMDP Fellowship for Endoscopic Ultrasound to the United Kingdom (St Thomas’ Hospital, University of London)
- HMDP Fellowship for invasive/interventional Endoscopy to Netherlands (Academic Medical Centre, University of Amsterdam
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Publications
- Role of fluorescence in situ hybridization in diagnosing cholangiocarcinoma in Indeterminate biliary strictures
Liew ZH, Loh TJZ, Lim TH, Khor CJL, Mesenas SJ, Kong CSC, Ong WC, Tan DMY
Journal of Gastroenterology and Hepatology 2017 - Steriod Responsive Mononeuritis Multiplex in the Cronkhite-Canada Syndrome
Y.L. Lo, K.H. Lim, X.M. Cheng and S.Mesenas
Frontiers In Neurology (November 2016, Vol 7, Article 207) - Management of biliary complications post liver transplant in Singapore
Yu Jun Wong, Hing Hieng Ngu, Mesenas Steven
Hepatol Int (2016 10 (Supp 1) S195) - Factors influencing treatment outcome in patients with gastroesophageal reflux disease; outcome of a prospective pragmatic trial in Asian patients
Khean Lee Goh, Kee Don Choi, Myung-Gyu Choi, Tsai-Yuan Hsieh, Hwoon-Yong Jung, Han-Chung Lien, Jayaram Menon, Steven Mesenas, Hyojin Park, Bor-Shyang Sheu and Justin CY Wu
BMC Gastroenterology 2014, 14:156 - Bilateral Adrenal Histoplasmosis: Endoscopic Ultrasound – guided Fine Needle Aspiration as a Method of Diagnosis and Assessment
J Khairul Azhar, H S G Jacqueline, L K H Tony, B H Tan, J M Steven
Medm J Malaysia Vol 66 No 5 December 2011 - Current status on the diagnosis and management of pancreatic cysts in the Asia-Pacific region: Role of endoscopic ultrasound
Lee Guan Lim, Takao Itoi, Wee Chian Lim, Steven Joseph Mesenas, Dong Wan Seo, Jonard Tan, Hsiu po Wang, Thawatchai Akaraviputh, Sandeep Lakhtakia, Salem Omar, Thawee Rantachu, Sharmila Sachitanandan, Kenjiro Yasuda, Shyam Varadarajulu, Jennie Wong, Vinay Dhir, Khek Yu Ho and the Asian Consortium of EUS
Journal of Gastroenterology and Hepatology, Vol 26, Issue 12, Pages 1702-1708, December 2011 - Guidelines on training and credentialing in endoscopic retrograde cholangiopancreatography
Ang T L, Cheng J, Khor J L C, Mesenas S J, Vu K F C, Wong W K
Singapore Medical Journal, September 2011, Vol 52 (9):654-657 - Guidelines for Endoscopic Ultrasonography
Steven Mesenas, Tiing Leong Ang, Christopher Khor, Charles Vu
Ann Acad Med Singapore 2010; 39 (6):489-492 - Ampullary carcinoma: Effect of preoperative biliary drainage on surgical outcome
Sheikh Anwar Abdullah, Tarun Gupta, Khairul Azhar Jaafar, Yaw Fui Alexander Chung, London Lucien Peng Jin Ooi, Steven Joseph Mesenas
World J Gastroenterol 2009; 15(23): 2908-2912 - Is there a place for N.O.T.E.S. in the diagnosis and treatment of neoplastic lesions of the pancreas?
Pasupathy S., Goh B.K.P., Shrikhande S.V., Mesenas S.J.
Surgical Oncology 2009; 18:139-146 - Carcinoma of ampulla of Vater: effect of preoperative biliary drainage on outcome Of Surgery
SA Abdullah, T Gupta, A Chung, LL Ooi, S Mesenas
Gastroenterology, volume 134, Issue 4, Supplement 1, April 2008, Pages A-456
Journal of Gastroenterology and Hepatology, Vol 23, Supplement 5, September 2008, AB 144 - EUS for Choledocholithiasis: accuracy and cost benefit analysis
Tarun Gupta, Sheikh Anwar Abdullah, Steven Mesenas
Gastrointestinal Endoscopy, Volume 67, Issue 5, April 2008, Page AB212
Journal of Gastroenterology and Hepatology, Vol 23, Supplement 5, September 2008, AB 143 - Multi-Center, Feasibility Study On the Use of An EUS Delivered P32-Labeled Liquid Based Brachytherapy Implant in Advanced Pancreatic Cancer
John Meenan, Steven Mesenas, Brinder Mahon, Pierce K. Chow, Kian Fong Foo, Anthony Goh, Sarah J. Heatley
Gastrointestinal Endoscopy, Volume 67, Issue 5, April 2008, Page AB109
Journal of Gastroenterology and Hepatology, Vol 23, Supplement 5, September 2008, AB 141 - A large series, resection controlled study to access the value of radial EUS in restaging gastroesophageal cancer following neoadjuvant chemotherapy
S Mesenas, C Vu, M McStay, M Forshaw, L Doig, R Mason, N Boyle, J Meenan
Diseases of the Esophagus 2008; Vol 21(1):37-42 - Gastric Antral Vascular Ectasia Successfully Controlled by Argon Plasma Coagulation.
B S Yew, K Y Ng, D S W Ang, S J Mesenas, C K Yap
Ann Acad Med Singapore 2007; 36 (8):702-703 - Pancreatic cysts : a proposed management algorithm based on current evidence
Brian K P Goh, Y M Tan, Y F S Chung, P K H Chow, P C Cheow, C H Thng, Steven Mesenas, W K Wong, L L P J Ooi
AM J of Surgery 2007; 193: 749-755 - EUS-Delivered Therapy for Pancreatic Cancer: Initial Experience with Targeted Injection of 32P Biosilicon
John Meenan, Steven Mesenas, Nivea Douglas, Sarah Hatley, Laura Doig, Paul Ross
Gastroint Endosc 2007;65(5):AB 208 - Value of EUS to Identify Thickening of the Extra-hepatic Biliary Tree Wall in Primary Sclerosing Cholangitis
Steven Mesenas, Charles Vu, Laura Doig, John Meenan
Gastrointest Endosc 2006; 63(5):AB 268 - Radial EUS for Re-staging Esophageal Cancer after Neo-adjuvant Chemotherapy predicts Survival but not Resectability: A Large Resection Controlled Study
Steven Mesenas, Charles Vu, Laura Doig, John Meenan
Gastrointest Endosc 2006; 63(5): AB257 - The role of EUS in the Management of Biliary and Pancreatic Disease
S J Mesenas
CME Gastroenterology 2006 ; 7(3):67-73 - Endoscopic Ultrasonography - Looking Beyond the Gastrointestinal Wall.
S J Mesenas
SGH Proceedings 2006; Vol 15:29-37 - Does the advent of Endoscopic Ultrasound(EUS) sound the Death Knell for Endoscopic Retrograde Cholangiopancreatography(ERCP)?
Steven J Mesenas
Ann Acad Med Singapore 2006; 35:89-95 - Duodenal EUS to identify thickening of the extrahepatic biliary tree wall in primary sclerosing cholangitis
S Mesenas, C Vu, L Doig, J Meenan
Gastrointest Endosc 2006; 63:403-8 - Irritable Bowel Syndrome – More Than Just Abdominal Pain.
S J Mesenas
SGH Proceedings 2005; Vol 14(1):68-74 - Molecular characterization of hepatitis B virus surface antigen mutants in Singapore patients with hepatocellular carcinoma with hepatitis B virus carriers negative for HBsAg but positive for anti-HBs and anti-HBc
C J Oon, W N Chen, K T Goh, S J Mesenas, H S Ng, G Chiang, C Tan, S Koh, S W Teng, I Toh, M C Moh, K S Goo, K Tan, A L Leong, G S Tan
Journal of Gastroenterology and Hepatology 2002; Vol 17( S4):S491 - Wild type and ‘a’ epitope variants in chronic Hepatitis B virus carriers positive for Hepatitis B surface antigen and antibody
S J Mesenas, W C Chow, Y Zhao, G K Lim, C J Oon, H S Ng
Journal of Gastroenterology and Hepatology 2002; Vol 17(2): 148-52 - Altered antigenicities of hepatitis B virus surface antigen carrying mutations outside the common ‘a’ determinant
W N Chen, C J Oon, I Toh, S J Mesenas , et al
American Journal of Gastroenterology 2000; Vol 95(4):1098-1105 - Primary leiomyoma of the Liver
S J Mesenas , K Y Ng, P Raj, J M S Ho, H S Ng
Singapore Medical Journal 2000;Vol 41(3):129-31 - Results of closed intra-articular calcaneal fractures treated with early mobilisation and without reduction
Low C K, Lam K S, S J Mesenas
Ann Acad Med Singapore 1995; 24(6):820-2
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Research Trials
- Use of Biomarkers to Detect Colorectal Cancer
- A Multi-Center Study of the Clinical Impact of EUS in Pancreatic Cancer Management in Asia
- ASEAN Registry of pancreatic cyst
- Azygos blood flow measurement by Doppler EUS: A novel tool to assess portal Haemodynamics
- B021128 RACHEL Study & B021129 MARK Study. Co-investigator
- Recurrent pyogenic cholangitis - diagnosis, patient characteristics, management and outcomes
- Transnasal Endoscopy : Utility in the placement of nasojejunal feeding tubes
- Endoscopic retrograde cholangiopancreatography in patients younger than 35 years old.
A case series - Endoscopic ultrasound guided celiac plexus neurolysis
- Gastric Cancer Epidemiology, Clinical and Genetics Programme (GCEP) Cohort Study of Patients at High risk of Gastric Cancer. Co-investigator
- Phase II Study of Neo-adjuvant Chemotherapy for Locally Advanced Gastric Cancer. The Singapore Gastric Cancer Cooperative Group. Co-investigator
- Comparison of post-surgical results of patients following curative surgery for Ampullary carcinoma with and without preoperative biliary drainage(endoscopic and percutaneous)
- The utility of endoscopic ultrasonography in the diagnosis and management algorithm of choledocholithiasis
- An open label, phase I/II safety and efficacy study of the active implantable radiological medical device 32P BioSilicon 30-micron High PW( 32P BioSilicon) administered at escalating levels of radioactivity to patients with locally advanced, unresectable pancreatic cancer, using endoscopic ultrasound guided fine needle implantation. Co-investigator
- A performance assessment of the use of an Olympus Ultrasonic Gastrovideoscope for Brachytherapy Implantation of non-radioactive BioSilicon 30 micron high pw in the pig pancreas. Co-investigator
- Treatment response in patients with symptoms due to gastroesophageal reflux disease either with or without esophagitis treated with pantoprazole sodium 40mg o.d. over 8 weeks
(REAL Life Study). Principal investigator, Singapore - Evaluating the clinical utility of radial endosonography in staging esophageal cancers following neoadjuvant chemotherapy
- Evaluation of radial endosonography in the diagnosis of extra-hepatic Primary Sclerosing Cholangitis
- A randomized, double-blind placebo-controlled, multicentre evaluation of the efficacy & safety of tegaserod (6mg bid) administered orally for 12 weeks, in male patients with chronic constipation. Principal Investigator, Singapore General Hospital
- Supportive Test for Acid-related symptoms (STARS-1 )with esomeprazole and a following 7-week, double-blind, randomized, placebo controlled treatment period in subjects with upper gastrointestinal symptoms and with normal findings at esophagastroduodenoscopy. Multicentre trial, co-investigator, Singapore General Hospital, Singapore
- Multicentre trial on the treatment of liver abscess – principal investigator for SGH
- Thymosin alpha-1 in a randomized controlled study in the treatment of chronic hepatitis B patients : Singapore experience (co-investigator)
- Alpha-fetoprotein differentiation L3 project (co-investigator) ’Wild Type’ & ‘a’ epitope variants in hepatitis B surface antigen and antibody positive hepatitis B carriers
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