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Dr Maria Noviani

BSc (Hons), MD, MMed (Internal Medicine), MRCP (UK), FAMS (Rheumatology)

Associate Consultant

Specialty: Rheumatology ＆ Immunology

Clinical Interest: Systemic Sclerosis

Clinical Appointments

Associate Consultant Rheumatology ＆ Immunology Singapore General Hospital
Visiting Consultant, Combined Pulmonary Hypertension Clinic, National Heart Centre Singapore National Heart Centre Singapore

Academic Appointments

Rheumatology Senior Residency Program – Physician Faculty
Adjunct Research Fellow, Duke-National University of Medical School, Singapore

Profile

Dr Maria Noviani is an Associate Consultant in the Department of Rheumatology and Immunology, Singapore General Hospital (SGH). She obtained her BSc (1st Class Hons) in Biological Sciences from Nanyang Technological University (Singapore) in 2010, MD degree from Duke-National University of Singapore Medical School (Singapore) in 2016. Following, she joined Membership of Royal College of Physicians (United Kingdom) in 2018 and was conferred MMed (Internal Medicine) in 2019. She completed her senior residency training in Rheumatology and Immunology (clinician-scientist track) at SingHealth in 2024 and was conferred Fellow of Academy Medicine of Singapore (Rheumatology) in 2024. She has recently embarked on PhD (Clinical and Translational Sciences) at Duke-National University of Singapore Medical School since 2023.

Dr Noviani has participated in scholarly activities since her undergraduate years. Her works have been recognised with various research awards, published in peer-reviewed research articles and presented at international conferences. More recently, Dr Noviani was awarded the National Medical Research Council (NMRC) Research Training Fellowship in 2023 to pursue translational research studies to investigate the peripheral immune landscape of systemic sclerosis.

Education

Master of Medicine (Internal Medicine), National University of Singapore, 2019
Membership of the Royal College of Physician (United Kingdom), 2018
Doctor of Medicine, Duke-National University of Singapore Medical School, Singapore, 2016
Bachelor of Science (1st Class Honours), School of Biological Sciences/ Nanyang Technological University, Singapore, 2010

Professional Appointments and Committee Memberships

Singapore Society of Rheumatologists – Member
Chapter of Rheumatologists, College of Physicians – Member

Awards

National Medical Research Council (NMRC) Research Training Fellowship, 2023
National Medical Research Council (NMRC) Clinician Scientist Resident Seed Funding, 2023
RiSE (Residency in SingHealth Excellence) Award, 2022
SingHealth Pitch for Fund, 2021
Academy of Medicine, Seah Cheng Siang Memorial Research Award, 2020
SingHealth Medical Student Talent Development Award, 2015
Singapore Chapter of Rheumatology, Feng Pao Hsii Prize in Rheumatology, 2014

Research Interests

Systemic sclerosis, connective tissue disease, clinical immunology

Publications

Ko J*, Noviani M*, Chellamuthu VR, Albani S, Low AHL. The Pathogenesis of Systemic Sclerosis: The Origin of Fibrosis and Interlink with Vasculopathy and Autoimmunity (*equal contribution as 1st author). International Journal of Molecular Sciences. 2023; 24(18):14287.
Noviani M, Vasuki C, Albani S, Low AHL. Molecular Stratification in SSc: towards Precision Medicine. Frontiers in Medicine. 2022; 9:911977.
Lee ZC, Noviani M, Yap J, et al. Tocilizumab for Systemic Sclerosis with Cardiac Involvement: A Case Report. Clinical and Experimental Rheumatology. 2022; 40(10):2006-2007.
Tan TC, Noviani M, Leung YY, Low AHL. The Microbiome and Systemic Sclerosis: A Review of Current Evidence. Best Practice & Research Clinical Rheumatology. 2021; 35(3):101687.
Noviani M, Feletar M, Nash P, Leung YY. Choosing the Right Treatment for Patient with Psoriatic Arthritis. Therapeutic Advances in Musculoskeletal Diseases. 2020. 12:1759720X20962623.
Noviani M, Saffari ES, Tan JL, Yip WLJ et al. Mortality and Hospitalization Outcomes of Interstitial Lung Disease and Pulmonary Hypertension in Systemic Sclerosis Cohort Singapore. Seminars in Arthritis and Rheumatism. 2020; 50(3): 473-479.
Leung YY, Ma S, Noviani M et al. Validation of Screening Questionnaires for Evaluation of Knee Osteoarthritis Prevalence in the General Population of Singapore. International Journal of Rheumatic Diseases. 2018; 21(3): 629-638.
Noviani M, Wasserman SD, Clowse MEB. Breastfeeding in Mothers with Systemic Lupus Erythematosus. Lupus. 2016; 25(9):973-979.
Noviani M, Jamiolkowski RM, Grenet JE, Lin Q et al. Rapid Seeding Ventricular Assist Device Sintered Titanium with Blood-Derived Endothelial Cells to Create a Living Antithrombotic Coating. American Society for Artificial Internal Organs Journal. 2016; 62(4): 447-453.
Jantzen AE, Noviani M, Mills JS, Baker KM et al. Point-of-Care Seeding of Nitinol Stents with Blood-Derived Endothelial Cells. Journal of Biomedical Materials Research Part B – Applied Biomaterials. 2016; 104(8): 1658-1665.
Noviani M, Eibel B, Jamiolkowski JM, Lin FH et al. Potential of Autologous Circulating CD34+45- Source Cells to Inhibit Smooth Muscle Cell Dedifferentiation for Intracranial and Vascular Stent Applications. International Journal of Advances in Science, Engineering and Technology. 2015; 3(3): 102-105.
Jamiolkowski RM, Kang SD, Rodriguez AK, Haseltine JM, Galinat LJ, Jantzen AE, Carlon TA, Darrabie MD, Arciniegas AJ, Mantilla JG, Haley NR, Noviani M et al. Increased Yield of Endothelial Cells from Peripheral Blood for Cell Therapies and Tissue Engineering. Regenerative Medicine. 2015; 10(4): 447-460.
Leung YY, Ang LW, Allen JC, Noviani M et al. Response to Letters to the Editors: 1. More Details on the Database Used by the Study Should be Provided. 2. MediClaim Hospital Discharge System and Income Levels of Cohort. Osteoarthritis and Cartilage. 2015; 23(3): 499-500.
Leung YY, Allen JC, Noviani M, Ang LW et al. Association between Body Mass Index and Risk of Total Knee Replacement, the Singapore Chinese Health Study. Osteoarthritis and Cartilage. 2015; 23(1): 41-47.