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Prof Terence Kee

Prof Kee Yi Shern Terence

MBBS (AUST), MRCP (UK), FRCP (UK), FAMS, FACP, FASN, FCoPM (Hon), FRPCT (Hon), FPCT (Hon), MSc (Transplantation) (UK), GDipHML

Senior Consultant

Specialty: Renal Medicine

Clinical Interest: Renal, Pancreas and Uterus Transplantation

Conditions Treated by this Doctor:
Kidney and Pancreas Transplant.

Clinical Appointments

  • Clinical Professor, Duke-NUS Medical School
  • Senior Consultant Renal Medicine Singapore General HospitalSingapore General Hospital
  • Program Director, Kidney Transplantation, SingHealth-Duke NUS Transplant Centre

Profile

Professor Terence Kee is a senior consultant renal physician with interest in kidney, pancreas, and uterus transplantation. He obtained his MBBS at the Flinders University of South Australia in 1994 and by 2000 completed the Singapore General Hospital basic and advanced physician training in general and renal medicine. He subsequently received a Singapore Government Human Manpower Development Program Award in 2004 to undergo a 1-year clinical fellowship in advanced renal transplantation under Professor Jeremy Chapman at the Westmead Hospital in Sydney, Australia. He returned to SGH in 2005 and became director of the kidney transplant program in 2008 ever since. 

Under his leadership, many milestones in kidney transplantation at SGH was achieved such as the first ABO-incompatible kidney transplant, the first dual deceased kidney donor transplant, the first ABO and HLA incompatible kidney transplant, paired kidney donor exchange and kidney transplantation using hepatitis B and human immunodeficiency virus positive kidney donors. New transplantation technologies and treatments were also introduced such as double filtration plasmaphresis, immunoadsorption and novel biologics to prevent and treat rejection of the kidney transplant. Professor Terence Kee also assisted in performing the first ABO-incompatible liver transplantation and assist in an advisory capacity for other transplant programs. Professor Terence Kee has also served in many leadership positions including Associate Program Director of the SingHealth Residency in Internal Medicine, Director of Clinical Service Planning and Special Projects for the Sengkang Hospital Planning Committee, Deputy Director of Research and Education at SingHealth Transplant and Clinical Director of Transplant Centre. He has also served as Chairman of the Chapter of Renal Physicians of Singapore, President of the Society of Transplantation of Singapore, President of the College of Physicians and sit as a council member of the Asian Society of Transplantation and the ASEAN Federation of Internal Medicine. Professor Terence Kee is also an academician, having published over 90 papers, a textbook in nephrology and a history book of the development of nephrology in Singapore. He has actively participated in industry and investigator sponsored studies with over a million dollars in grant funding. His current research interests are in clinical immunosuppression, novel biomarkers, and BK virus infection.  

In recognition for his contributions in public healthcare and medical education, Professor Terence Kee has received many awards notably the SingHealth Residency Outstanding Mentor Award (2011), the Yong Loo Lin School of Medicine Dean Award for Teaching Excellence (2013), SingHealth Residency Outstanding Faculty Award (2021), the National Day Long Service Award (2021) and the COVID Resilience Medal (2023). He was also awarded the Dr Lim Cheng Hong Lectureship (2022) and the Chapter of Renal Physician Lectureship (2023) in recognition of his contributions to nephrology in Singapore. Professor Terence Kee also received a SGH scholarship and is the first transplant physician in Singapore to complete a Master Degree in Transplantation Sciences from the University of Liverpool. After working hours, Professor Terence Kee contributes to the community by being a volunteer doctor at the Kidney Dialysis Foundation and organizing fund raising cycling events to raise funds for the SGH needy patient fund. In 2023, Professor Terence Kee founded Singapore’s first cycling team of transplant patients which represented Singapore at the World Transplant Games in 2023. 

Professor Terence Kee is also keen on advancing transplantation in Asia, having trained several fellows from South-East Asia in transplantation and is co-chair of the Asian Solid Organ Transplant Registry, having published several multinational studies of transplantation in Asia. He was also conferred honorary fellowships from the College of Physicians of Malaysia, Royal College of Physicians of Thailand and the Philippines College of Physicians in recognition of his contribution to foster academic medicine partnerships in the region.

Education

  • MBBS (Australia) 1995
  • MRCP (Edinburgh) 2000
  • FAMS (Renal Medicine) 2004
  • FRCP (Edinburgh) 2011
  • FASN (USA) 2012
  • FACP (USA) 2019
  • GDipHML (Singapore Management University) 2009
  • Master Degree in Transplantation Science (Liverpool University UK) 2024

Professional Appointments and Committee Memberships

Prof Terence Kee is currently Senior Consultant and Director of Kidney Transplantation at the Department of Renal Medicine. Prof Terence Kee is a visiting consultant at the Kidney Dialysis Foundation. He is also a clinical professor at the Duke NUS Medical School and faculty for the SingHealth Residency Program in Advanced Internal Medicine and Renal Medicine. He sits as a member of the MOH Kidney Transplant Advisory Committee, MOH Review Committee for Donor and Recipient Screening for Blood Borne Infections and Workgroup to Improve Living Kidney Donation in Singapore. Prof Terence Kee serve as an advisor in the Society of Transplantation of Singapore and is a council member of the Asian Transplantation Society. He is co-chair of the Asian Solid Organ Transplant Registry and chair of the SGH Transplant Ward Committee.  Prof Terence Kee serves as associate editor of the Transplantation Reviews and is a member of the Editorial Board of the Proceeding of Singapore Healthcare journal.

Awards

  • SGH Best Registry Oral Paper (2003)
  • MOH Human Manpower Development Award (2023)
  • Service with a heart award (2007, 2012, 2014, 2017, 2023
  • SingHealth quality award (2009, 2016, 2023)
  • SingHealth Residency Outstanding Mentor Award (2011)
  • Yong Loo Lin School of Medicine Dean Award for Teaching Excellence (2013)
  • SGH Scholarship Award (2017)
  • SingHealth Residency Outstanding Faculty Award (2021)
  • National Day Long Service Award (2021)
  • SingHealth Residency Faculty Appreciation Award (2022)
  • Dr Lim Cheng Hong Lectureship Medal (2022)
  • Chapter of Renal Medicine Lectureship (2023)

Research Interests

  • Clinical Immunosuppression
  • Biomarkers in transplantation
  • BK virus

Publications

  • Kee TY, Chapman JR, O'Connell PJ, Fung CL, Allen RD, Kable K, Vitalone MJ, Nankivell BJ. Treatment of subclinical rejection diagnosed by protocol biopsy of kidney transplants. Transplantation. 2006 Jul 15;82(1):36-42. 
  • Meng OY, Lim C, Leng CW, van der Erf S, Joshi VD, Sin ST, Hong ST, Chye PG, Seng GT, Yi-Shern TK. Factors influencing living kidney donation in Singapore. Prog Transplant. 2012 Mar;22(1):95-101. 
  • Tan CS, Loh HL, Foo MW, Choong LH, Wong KS, Kee TY. Epstein-Barr virus-associated smooth muscle tumors after kidney transplantation: treatment and outcomes in a single center. Clin Transplant. 2013 Jul-Aug;27(4):E462-8. 
  • Kwek JL, Tey V, Yang L, Kanagalingam D, Kee T. Renal and obstetric outcomes in pregnancy after kidney transplantation: Twelve-year experience in a Singapore transplant center. J Obstet Gynaecol Res. 2015 Sep;41(9):1337-44. doi: 10.1111/jog.12736. Epub 2015 May 28. PMID: 26017543.
  • Fong NJM, Fan PYW, Fook-Chong SMC, Kee TYS. The effect of pre-operative methylprednisolone on the incidence of delayed graft function in renal transplantation. Proceedings of Singapore Healthcare. 2016;25(2):122-126. 
  • Teo SH, Lee KG, Lim GH, Koo SX, Ramirez ME, Chow KY, Kee T. Incidence, risk factors and outcomes of malignancies after kidney transplantation in Singapore: a 12-year experience. Singapore Med J. 2019 May;60(5):253-259. 
  • Ho QY, Lim CC, Thangaraju S, Siow B, Chin YM, Hao Y, Lee PH, Foo M, Tan CS, Kee T. Bleeding Complications and Adverse Events After Desmopressin Acetate for Percutaneous Renal Transplant Biopsy. Ann Acad Med Singap. 2020 Feb;49(2):52-64. 
  • Tan MSH, Chung SJ, Ho QY, Thangaraju S, Kee TYS. A single-centre observational study comparing the impact of different cytomegalovirus prophylaxis strategies on cytomegalovirus infections in kidney transplant recipients. Proceedings of Singapore Healthcare. 2021;30(2):117-124. doi:10.1177/2010105820953461
  • Kee T, Jeong JC, Ur-Rashid H, Begum NAS, Arakama MH, Danguilan R, Od-Erdene L, Yahya R, Kim Y, Sran HK, Ma B, Ma M, Rana DS, Ahn C, Ahmad G. Clinical characteristics, outcomes, and management of COVID-19 in kidney transplant recipients across Asia: an ASTREGO report. Korean J Transplant. 2021 Dec 31;35(4):218-229. 
  • Vijayan S, Ho QY, Koh CH, Liew IT, Thangaraju S, Wong N, Keh YS, Ong ZHS, Tan JQ, Yeo KK, Chua TSJ, Kee T. Cardiac evaluation for end-stage kidney disease patients on the transplant waitlist: a single-center cohort study. Korean J Transplant. 2022 Sep 30;36(3):187-196. 
  • Ho QY, Lai CMD, Liew WIT, Oon LLE, Lim KL, Chung SJ, Thangaraju S, Tien SC, Tan CS, Kee T. Immune monitoring of prevalent kidney transplant recipients using Torque Teno Virus: Protocol for a single-centre prospective cohort study. BMJ Open 2023 Sept 19; 13(9): e076122. doi: 10.1136/bmjopen-2023-076122.
  • Ho QY, Phang CY, Liew IT, Lai ML, Tien CS, Thangaraju S, Kee T. Unrepresented human leucocyte antigen alleles in single-antigen bead assays: a single-centre cohort study. Int J Immunogenet 2023; 50(6): 306-315.

Research Trials