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Dr Daphne Gardner Su Lyn

BA (Physiological Sciences), BM BCh (Oxon), MRCP (UK), FRCP (Edin)

Senior Consultant

Singapore General Hospital

Specialty: Endocrinology, Endocrinology

Clinical Interest: General Endocrinology, Young Adults with Diabetes, Diabetes Technology, Type 1 Diabetes, Monogenic Diabetes

Conditions Treated by this Doctor:
Type 1 Diabetes Mellitus (T1DM), Type 2 Diabetes Mellitus.

Clinical Appointments

Director, Education SingHealth Duke-NUS Diabetes Centre
Senior Consultant Endocrinology Singapore General Hospital

Academic Appointments

Clinical Senior Lecturer, Yong Loo Lin School of Medicine, Singapore
Duke-NUS Graduate Medical School

Profile

Dr Daphne Gardner is a Senior Consultant in Endocrinology in Singapore General Hospital. She graduated from Oxford University (UK) and was a clinical lecturer in Plymouth (UK) before attaining specialist accreditation in Endocrinology in Singapore. Her fellowship year was spent in the Oxford Centre for Diabetes, Endocrinology and Metabolism, UK. She is the lead clinician for the Young Adults with Diabetes and intensive insulin therapy programme in Singapore General Hospital.

She is on the physician faculty for the SingHealth Endocrinology senior residency programme and Director of Education in the SingHealth-Duke Disease Centre for Diabetes. She has held 2 grants aimed at stratifying diabetes to direct personalised therapy and was a member of the workgroup involved in the MOH clinical practice guidelines on diabetes.

Education

• FRCP, Edinburgh

• Advanced specialty training in Endocrinology, Singapore

• MRCP (UK), London

• BM BCh, St John’s College, Oxford

• BA in Physiological Sciences, St John’s College, Oxford

Professional Appointments and Committee Memberships

• Fellow, Royal College of Physicians, Edinburgh

Awards

• Service with a heart award, Singapore General Hospital, 2015

• Stratified Medicine Programme Office Invited Research Grant, 2013

• SingHealth Foundation research grant, 2013

• Service with a heart award, Singapore General hospital, 2012

• HMDP Award Fellowship in Oxford, UK, 2012

• Service Quality Partners Award, Singapore General Hospital, 2009

• Best oral presentation ADDDG meeting, Holland, 2006

• Tan Chin Tuan Medal Singapore, 1995

• Ministry of Education Scholarship, Singapore, 1994

Research Interests

Publications

Incremental Cost-effectiveness of Algorithm-Driven Genetic Testing versus No Testing for Maturity Onset Diabetes of the Young (MODY) in Singapore. Nguyen VH, Finkelstein E, Mital S, Gardner DSL. Journal of Medical Genetics, 2017; Nov, 54 (22): 747-753.

Psychometric validation of the Hypoglycemia Fear Survery-II (HFS-II) in Singapore. Lam AYR, Xin X, Tan WB, Gardner DSL, Goh SY. BMJ Open Diabetes Research and Care, June 2017, doi:10.1136/bmjdrc-2016-000329

Recessively Inherited Lrba Mutations Cause Autoimmunity Presenting as Neonatal Diabetes. Johnson MB, De Franco E, Lango-Allen H, Al Senani A, Elbarbary N, Siklar Z, Berberoglu M, Imane Z, Haghighi A, Ullah I, Alyaarubi S, Gardner D, Ellard S, Hattersley AT, Flanagan SE. Diabetes. 2017 May 4

A rare cause of hyperthyroidism: functioning thyroid metastases. D Gardner, SC Ho. BMJ Case Reports. 2014 Oct 9.

Clinical features and treatment of Maturity Onset Diabetes of the Young. DS Gardner, Tai ES. Diabetes, Metabolic Syndrome and Obesity 2012; 5:101-108.

Paraganglioma with Acute Hyperamylasemia Masquerading as Acute Pancreatitis. ET Ho, DS Gardner. Singapore Medical Journal, Dec 2011; 52(12):e251-4.

Ethnicity modifies the relationships of insulin resistance, inflammation, and adiponectin with obesity in a multiethnic asian population. Khoo CM, Sairazi S, Taslim S, Gardner D, Wu Y, Lee J, van Dam RM, Shyong Tai E. Diabetes Care, 2011 May; 34(5): 1120-6.

Genetic variation in KCNQ1 associates with fasting glucose and beta-cell function: a study of 3734 subjects comprising three ethnicities living in Singapore. Tan JT, Nurbaya S, Gardner D, Sandra Y, Tai ES, NG DP. Diabetes. 2009 Jun;58(6):1445-9.

An unusual outbreak of hypoglycaemia. Kao SL, Chan CL, Tan B, Lim CC, Dalan R, Gardner D, Pratt E, Lee M, Lee KO. NEJM , 2009 Feb 12; 360 (7): 734-6.

Contribution of early weight gain to childhood overweight and metabolic health: a longitudinal study. (Earlybird 36) Gardner DS-L, Hosking J, Metcalf BS, Jeffery AN, Voss LD, Wilkin TJ. Pediatrics. 2009 Jan;123(1):e67-73

Trends, Associations and Predictions of Insulin Resistance in Prepubertal Children. (EarlyBird 29) Gardner DS-L, Metcalf BS, Hosking J, Jeffery AN, Voss LD, Wilkin TJ. Pediatric Diabetes, 2008, June; 9(3 Pt 1): 214-220.

Clinical Manifestations of familial paraganglioma and phaeochromocytoma in succinate dehydrogenase B gene mutation carriers. Srirangalingam U, Walker L, Khoo B, Macdonald F, Gardner D, Wilkin TJ, Skelly RH, George E, Spooner D, Monson JP, Grossman AB, Akker SA, Pollard PJ, Plowman N, Avril N, Berney DM, Burrin JM, Reznek RH, Kumar VK, Maher ER, Chew SL. Clinical Endocrinology, 2008, Oct, 69(4): 587-96.

Increased urinary Dopamine excretion in association with bilateral carotid body tumours—clinical, biochemical and genetic findings. Jeffery J, Devendra D, Farrugia J, Gardner D, Murphy MJ, Williams R, Ayling RM, Wilkin TJ. Annals of Clinical Biochemistry 2006, Mar 43 (Pt 2):156-60.

Resting energy expenditure, adiponectin and changes in body composition of young children (EarlyBird 34). Hosking J, Metcalf BS, Jeffery AN, Gardner D, Voss LD, Wilkin TJ, Int J Paediatr Obes, 2007, Aug 29: 1-6.

The behaviour of insulin resistance and its metabolic correlates in pre-pubertal children: a longitudinal study (EarlyBird 32). Jeffery AN, Alba S, Muphy MJ, Voss LD, Metcalf BS, Hosking J, Gardner DS, Sattar N, Wilkin TJ. Diabetes Care 2007, Nov 30(11): 2962-2964.