Q: I am a 60-year-old male recently diagnosed with Transthyretin Amyloid Cardiomyopathy (ATTR-CM). What are my treatment options? Is this disease curable?
A: In general, the treatment for ATTR-CM can be divided into two aspects.
First, there is the supportive treatment of heart failure, as well as electrical conduction block and rhythm disorders, which arise from the deposition or infiltration of abnormal transthyretin (TTR) protein into different parts of the heart — such as the heart valves or muscle.
Second, there are specific treatment agents that try to prevent or reduce this abnormal protein from depositing into the heart, significantly the heart muscle, along with agents that help to remove them from the heart.
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