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Centre for Assisted Reproduction
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Our Assisted Reproductive Services
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Centre for Assisted Reproduction
Our Assisted Reproductive Services
Fertility Preservation
Regulatory and Funding
FAQs about Fertility
IVF Journey: Oocyte Retrieval (Egg Collection)
IVF Journey: Post Embryo Transfer
> Obstetrics and Gynaecology
> Neonatal & Developmental Medicine
Page Content
Basic Ovulation Monitoring (ROM)
This is performed to assess ovulation, i.e. to identify the ideal time to try for a pregnancy.
Tests include a series of ultrasound scans to look at the size of the follicle containing eggs, or use of urine strips which you can test by yourself. Hormone injections may be necessary to promote final maturation of the follicle containing the eggs. This may be done in combination with IUI.
Induction of Ovulation
Clomiphene or Letrozole are oral medications used to stimulate hormones to promote growth of the eggs. It may take several cycles to find the right dosage.
Parenteral Induction of Ovulation (PIO)
PIO is another form of ovulation induction where hormone injections are used instead of oral medication. It is used when a patient fails to respond to oral medication and the fallopian tubes are functioning. It is usually combined with Intra-uterine Insemination (IUI).
What to expect
Daily injections for about 2 weeks to stimulate the development of 1 to 3 follicles in the ovary.
Serial ultrasound scans and blood tests may be performed.
When largest follicle (containing the egg) is deemed ready, an injection is given to release the egg.
IUI is usually performed 1 day after the injection.
Urine pregnancy test will be performed about 2 weeks after ovulation.
The cycle may be abandoned if too many or no eggs are produced.
Intra-uterine Insemination (IUI)
This involves introducing processed sperm into the womb through a fine catheter during ovulation. Doctor will assess and screen the suitability for couple prior to selection for IUI.
What to expect
Success rate is approximately 5% per cycle
IUI is usually done in combination with BOM, use of Clomiphene, Letrozole or PIO (see above).
This is an outpatient procedure that takes about 20 minutes and is similar to a Pap smear.
On the day of IUI, the husband needs to provide a semen sample in the morning.
Advanced Procedures
In-Vitro Fertilisation (IVF)
Hormonal injections are given for about 2 to 4 weeks to stimulate the follicle containing eggs in the ovary. Eggs are then collected and inseminated or injected with the husband’s sperm in the laboratory. After fertilisation, the embryos are incubated for a few days before being placed into the womb. A successful pregnancy can be confirmed two weeks later.
Intra-Cytoplasmic Sperm Injection (ICSI)
ICSI involves injecting a single sperm into each egg to allow fertilization to occur in the laboratory. This is recommended if the man has poor quality sperm or if there had been dificulties with fertilization in the past.
Blastocyst Culture
In this procedure, embryos are cultured for 5 days to become a blastocyst. The chances of pregnancy are much higher with a blastocyst transfer. This is suitable for those with repeated IVF failure, multiple eggs and those who need Pre-implantation Genetic Diagnosis.
Other services
Your doctor will discuss the following options with you if you are deemed suitable.
In-vitro maturation of oocytes
Embryo, egg and sperm cryopreservation
Donor sperm, egg, embryo programs
Pre-implantation Genetic Diagnosis (PGD)
Pre-implantation Genetic Screening (PGS)
Workflow for IVF
Patient can find out more with our Call Centre hotline (+65 6321 4377).
6/11/2019 3:45 PM
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